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Systematic review of randomized controlled trials on interventions for melasma: An abridged Cochrane review

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Conservative protocols involving cycling address this uncertainty by limiting continuous exposure

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This pattern is consistent with a healthy-user bias, whereby individuals who are younger and generally healthier tend to experience more favorable outcomes regardless of treatment exposure

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Metformin inhibits the production of reactive oxygen species from NADH:ubiquinone oxidoreductase to limit induction of interleukin-1 (IL-1) and boosts interleukin-10 (IL-10) in lipopolysaccharide (LPS)-activated macrophages

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